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Target
Somatostatin receptor type 3
Ligand
BDBM50136763
Substrate
n/a
Meas. Tech.
ChEMBL_200692 (CHEMBL807102)
IC50
273±n/a nM
Citation
 Rivier, J; Erchegyi, J; Hoeger, C; Miller, C; Low, W; Wenger, S; Waser, B; Schaer, JC; Reubi, JC Novel sst(4)-selective somatostatin (SRIF) agonists. 1. Lead identification using a betide scan. J Med Chem 46:5579-86 (2003) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 3
Synonyms:
SOMATOSTATIN SST3 | SS-3-R | SS3-R | SS3R | SSR-28 | SSR3_HUMAN | SSTR3 | Somatostatin receptor type 3 (SSTR3)
Type:
Protein
Mol. Mass.:
45855.97
Organism:
Homo sapiens (Human)
Description:
P32745
Residue:
418
Sequence:
MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL
  
Inhibitor
Name:
BDBM50136763
Synonyms:
(4S,7R,10S,13R,16S,20R,23R,26S)-26-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]-13-(4-aminobutyl)-7,23-dibenzyl-4-carboxy-10-[(1R)-1-hydroxyethyl]-16-(1H-indol-3-ylmethyl)-19-methyl-6,9,12,15,18,22,25-heptaoxo-1,2-dithia-5,8,11,14,17,19,21,24-octaazacycloheptacosan-20-olate | Peptide analogue
Type:
Small organic molecule
Emp. Form.:
C57H71N12O13S2
Mol. Mass.:
1196.377
SMILES:
C[C@@H](O)[C@@H]1NC(=O)[C@@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)N(C)[C@H]([O-])NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CSSC[C@@H](NC(=O)[C@@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1
Structure:
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