Reaction Details Report a problem with these data
Target
Malate dehydrogenase
Ligand
BDBM50310357
Substrate
n/a
Meas. Tech.
ChEMBL_103875 (CHEMBL712992)
IC50
60000±n/a nM
Citation
 McGovern, SL; Shoichet, BK Kinase inhibitors: not just for kinases anymore. J Med Chem 46:1478-83 (2003) [PubMed]  Article 
Target
Name:
Malate dehydrogenase
Synonyms:
MDH_THETH | mdh
Type:
PROTEIN
Mol. Mass.:
35423.44
Organism:
Thermus thermophilus
Description:
ChEMBL_1448377
Residue:
327
Sequence:
MKAPVRVAVTGAAGQIGYSLLFRIAAGEMLGKDQPVILQLLEIPQAMKALEGVVMELEDCAFPLLAGLEATDDPKVAFKDADYALLVGAAPRKAGMERRDLLQVNGKIFTEQGRALAEVAKKDVKVLVVGNPANTNALIAYKNAPGLNPRNFTAMTRLDHNRAKAQLAKKTGTGVDRIRRMTVWGNHSSTMFPDLFHAEVDGRPALELVDMEWYEKVFIPTVAQRGAAIIQARGASSAASAANAAIEHIRDWALGTPEGDWVSMAVPSQGEYGIPEGIVYSFPVTAKDGAYRVVEGLEINEFARKRMEITAQELLDEMEQVKALGLI
  
Inhibitor
Name:
BDBM50310357
Synonyms:
CHEMBL599552 | indigo
Type:
Small organic molecule
Emp. Form.:
C16H10N2O2
Mol. Mass.:
262.2628
SMILES:
O=C1C(Nc2ccccc12)=C1Nc2ccccc2C1=O |w:2.2|
Structure:
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