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Target
Beta-amylase
Ligand
BDBM50174838
Substrate
n/a
Meas. Tech.
ChEMBL_326643 (CHEMBL868728)
IC50
126800±n/a nM
Citation
 Seo, WD; Kim, JH; Kang, JE; Ryu, HW; Curtis-Long, MJ; Lee, HS; Yang, MS; Park, KH Sulfonamide chalcone as a new class of alpha-glucosidase inhibitors. Bioorg Med Chem Lett 15:5514-6 (2005) [PubMed]  Article 
Target
Name:
Beta-amylase
Synonyms:
AMYB | AMYB_HORVU | BMY1
Type:
PROTEIN
Mol. Mass.:
59640.69
Organism:
Hordeum vulgare
Description:
ChEMBL_326643
Residue:
535
Sequence:
MEVNVKGNYVQVYVMLPLDAVSVNNRFEKGDELRAQLRKLVEAGVDGVMVDVWWGLVEGKGPKAYDWSAYKQLFELVQKAGLKLQAIMSFHQCGGNVGDAVNIPIPQWVRDVGTRDPDIFYTDGHGTRNIEYLTLGVDNQPLFHGRSAVQMYADYMTSFRENMKDFLDAGVIVDIEVGLGPAGEMRYPSYPQSHGWSFPGIGEFICYDKYLQADFKAAAAAVGHPEWEFPNDVGQYNDTPERTQFFRDNGTYLSEKGRFFLAWYSNNLIKHGDRILDEANKVFLGYKVQLAIKISGIHWWYKVPSHAAELTAGYYNLHDRDGYRTIARMLKRHRASINFTCAEMRDLEQSSQAMSAPEELVQQVLSAGWREGLNVACENALPRYDPTAYNTILRNARPHGINQSGPPEHKLFGFTYLRLSNQLVEGQNYVNFKTFVDRMHANLPRDPYVDPMAPLPRSGPEISIEMILQAAQPKLQPFPFQEHTDLPVGPTGGMGGQAEGPTCGMGGQVKGPTGGMGGQAEDPTSGIGGELPATM
  
Inhibitor
Name:
BDBM50174838
Synonyms:
1-(4-aminophenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one | CHEMBL200485
Type:
Small organic molecule
Emp. Form.:
C15H13NO3
Mol. Mass.:
255.2686
SMILES:
Nc1ccc(cc1)C(=O)\C=C\c1ccc(O)c(O)c1
Structure:
Search PDB for entries with ligand similarity: