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Target
Nociceptin receptor
Ligand
BDBM50189257
Substrate
n/a
Meas. Tech.
ChEMBL_378705 (CHEMBL853453)
Ki
0.300000±n/a nM
Citation
 Crooks, PA; Kottayil, SG; Al-Ghananeem, AM; Byrn, SR; Butterfield, DA Opiate receptor binding properties of morphine-, dihydromorphine-, and codeine 6-O-sulfate ester congeners. Bioorg Med Chem Lett 16:4291-5 (2006) [PubMed]  Article 
Target
Name:
Nociceptin receptor
Synonyms:
OOR | OPRL1 | OPRX_CAVPO
Type:
PROTEIN
Mol. Mass.:
40796.89
Organism:
Cavia porcellus
Description:
ChEMBL_444577
Residue:
370
Sequence:
MESLFPAPFWEVLYGSHLQGNLSLLSPNHSGLPPHLLLNASHSAFLPLGLKVTIVGLYLAVCIGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQATDILLGFWPFGNTLCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALALVVGVPVAIMGSAQVEDEEIECLVEIPDPQDYWGPVFAVSIFLFSFIIPVLIISVCYSLMIRRLHGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLVQGLGVQPGSETTVAILRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALHREMQVSDRVRSIAKDVALGCKTTETVPRPA
  
Inhibitor
Name:
BDBM50189257
Synonyms:
CHEMBL378753 | NalBzOH
Type:
Small organic molecule
Emp. Form.:
C26H27N3O4
Mol. Mass.:
445.5103
SMILES:
Oc1ccc2CC3N(CC=C)CCC45[C@H](Oc1c24)C(CCC35O)=NNC(=O)c1ccccc1 |w:23.28,TLB:22:21:7.11.12:17.5.4,THB:8:7:21:17.5.4,16:17:21:7.11.12|
Structure:
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