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Target
Nociceptin receptor
Ligand
BDBM50189249
Substrate
n/a
Meas. Tech.
ChEMBL_378705 (CHEMBL853453)
Ki
266±n/a nM
Citation
 Crooks, PA; Kottayil, SG; Al-Ghananeem, AM; Byrn, SR; Butterfield, DA Opiate receptor binding properties of morphine-, dihydromorphine-, and codeine 6-O-sulfate ester congeners. Bioorg Med Chem Lett 16:4291-5 (2006) [PubMed]  Article 
Target
Name:
Nociceptin receptor
Synonyms:
OOR | OPRL1 | OPRX_CAVPO
Type:
PROTEIN
Mol. Mass.:
40796.89
Organism:
Cavia porcellus
Description:
ChEMBL_444577
Residue:
370
Sequence:
MESLFPAPFWEVLYGSHLQGNLSLLSPNHSGLPPHLLLNASHSAFLPLGLKVTIVGLYLAVCIGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQATDILLGFWPFGNTLCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALALVVGVPVAIMGSAQVEDEEIECLVEIPDPQDYWGPVFAVSIFLFSFIIPVLIISVCYSLMIRRLHGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLVQGLGVQPGSETTVAILRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALHREMQVSDRVRSIAKDVALGCKTTETVPRPA
  
Inhibitor
Name:
BDBM50189249
Synonyms:
CHEMBL211576 | M3IBu6S
Type:
Small organic molecule
Emp. Form.:
C21H25NO7S
Mol. Mass.:
435.491
SMILES:
CC(C)C(=O)Oc1ccc2C[C@@H]3[C@@H]4C=C[C@H](OS([O-])(=O)=O)[C@@H]5Oc1c2[C@]45CC[NH+]3C |c:13,TLB:23:24:12:28.26.27,8:9:12:28.26.27|
Structure:
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