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Target
Bcl2-associated agonist of cell death
Ligand
BDBM50202277
Substrate
n/a
Meas. Tech.
ChEMBL_464767 (CHEMBL930133)
Ki
5250±n/a nM
Citation
 Wang, L; Kong, F; Kokoski, CL; Andrews, DW; Xing, C Development of dimeric modulators for anti-apoptotic Bcl-2 proteins. Bioorg Med Chem Lett 18:236-40 (2008) [PubMed]  Article 
Target
Name:
Bcl2-associated agonist of cell death
Synonyms:
BAD | BAD_HUMAN | BBC6 | BCL2L8 | Bcl-2-binding component 6 | Bcl-2-like protein 8 | Bcl-XL/Bcl-2-associated death promoter | Bcl2 antagonist of cell death | Bcl2-L-8 | Bcl2-antagonist of cell death (BAD)
Type:
PROTEIN
Mol. Mass.:
18393.69
Organism:
Homo sapiens (Human)
Description:
ChEMBL_478760
Residue:
168
Sequence:
MFQIPEFEPSEQEDSSSAERGLGPSPAGDGPSGSGKHHRQAPGLLWDASHQQEQPTSSSHHGGAGAVEIRSRHSSYPAGTEDDEGMGEEPSPFRGRSRSAPPNLWAAQRYGRELRRMSDEFVDSFKKGLPRPKSAGTATQMRQSSSWTRVFQSWWDRNLGRGSSAPSQ
  
Inhibitor
Name:
BDBM50202277
Synonyms:
(S)-2-(5-(4-bromobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)-3-phenylpropanoic acid | 2-[5-(4-bromobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl]-3-phenylpropanoic acid | CHEMBL243190 | Thiazolidinone core, 24
Type:
Small organic molecule
Emp. Form.:
C19H14BrNO3S2
Mol. Mass.:
448.353
SMILES:
OC(=O)[C@H](Cc1ccccc1)N1C(=S)S\C(=C/c2ccc(Br)cc2)C1=O
Structure:
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