Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50265754
Substrate
n/a
Meas. Tech.
ChEMBL_560595 (CHEMBL1022320)
Ki
30±n/a nM
Citation
 Markt, P; Feldmann, C; Rollinger, JM; Raduner, S; Schuster, D; Kirchmair, J; Distinto, S; Spitzer, GM; Wolber, G; Laggner, C; Altmann, KH; Langer, T; Gertsch, J Discovery of novel CB2 receptor ligands by a pharmacophore-based virtual screening workflow. J Med Chem 52:369-78 (2009) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50265754
Synonyms:
(6-methoxynaphthalen-1-yl)(2-methyl-1-propyl-1H-indol-3-yl)methanone | CHEMBL522550 | JWH-151
Type:
Small organic molecule
Emp. Form.:
C24H23NO2
Mol. Mass.:
357.4449
SMILES:
CCCn1c(C)c(C(=O)c2cccc3cc(OC)ccc23)c2ccccc12
Structure:
Search PDB for entries with ligand similarity: