Reaction Details Report a problem with these data
Target
Cdc2
Ligand
BDBM27216
Substrate
n/a
Meas. Tech.
ChEMBL_563793 (CHEMBL994305)
IC50
500±n/a nM
Citation
 Gray, NS; Wodicka, L; Thunnissen, AM; Norman, TC; Kwon, S; Espinoza, FH; Morgan, DO; Barnes, G; LeClerc, S; Meijer, L; Kim, SH; Lockhart, DJ; Schultz, PG Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors. Science 281:533-538 (1998) [PubMed]  Article 
Target
Name:
Cdc2
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
34220.62
Organism:
Asterina pectinifera
Description:
ChEMBL_563793
Residue:
300
Sequence:
MEDYSKIEKIGEGTYGVVYKGRCKKDGSIVALKKIRLESEEEGVPSTAIREISLLKELQHPNVVNLSNVLMQESRLYLVFEFLTMDLKKYMETLRGTTMDPALVKSYLHQIVQGILFCHCRRVLHRDLKPQNLLIDEKGIIKLADFGLARAFGIPVRVYTHEVVTLWYRAPEVLLGSPRYSTPVDVWSIGCIFAEMVTKRPLFHGDSEIDQLFRIFRTPGTPTDKTWPGVTELPDHKSTFPKWTTNNLAKSVKTLTLRNDLLQKMLIYDPAKRISCKAALSHPYLKDFEGGTVLPTRLGQ
  
Inhibitor
Name:
BDBM27216
Synonyms:
(2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)-9H-purin-2-yl}amino)-3-methylbutan-1-ol | 2,6,9-Trisubstitute purine, 1 | CHEMBL23327 | Purvalanol A
Type:
Small organic molecule
Emp. Form.:
C19H25ClN6O
Mol. Mass.:
388.894
SMILES:
CC(C)[C@H](CO)Nc1nc(Nc2cccc(Cl)c2)c2ncn(C(C)C)c2n1
Structure:
Search PDB for entries with ligand similarity: