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Target
Cyclin-dependent protein kinase PHO85
Ligand
BDBM50267719
Substrate
n/a
Meas. Tech.
ChEMBL_563813 (CHEMBL994325)
IC50
>500000±n/a nM
Citation
 Gray, NS; Wodicka, L; Thunnissen, AM; Norman, TC; Kwon, S; Espinoza, FH; Morgan, DO; Barnes, G; LeClerc, S; Meijer, L; Kim, SH; Lockhart, DJ; Schultz, PG Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors. Science 281:533-538 (1998) [PubMed]  Article 
Target
Name:
Cyclin-dependent protein kinase PHO85
Synonyms:
Cyclin-dependent protein kinase PHO85 | PHO85 | PHO85_YEAST | Pho80/Pho85 | SSG3
Type:
PROTEIN
Mol. Mass.:
34912.85
Organism:
Saccharomyces cerevisiae
Description:
ChEMBL_563813
Residue:
305
Sequence:
MSSSSQFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVTKLPKYNPNIQQRPPRDLRQVLQPHTKEPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWFAEYYHHAS
  
Inhibitor
Name:
BDBM50267719
Synonyms:
2-(6-((3-chlorophenyl)(methyl)amino)-9-isopropyl-9H-purin-2-ylamino)ethanol | CHEMBL519036
Type:
Small organic molecule
Emp. Form.:
C17H21ClN6O
Mol. Mass.:
360.841
SMILES:
CC(C)n1cnc2c(nc(NCCO)nc12)N(C)c1cccc(Cl)c1
Structure:
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