Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM50322245
Substrate
n/a
Meas. Tech.
ChEMBL_642590 (CHEMBL1176479)
Ki
1585±n/a nM
Citation
 Vangveravong, S; Taylor, M; Xu, J; Cui, J; Calvin, W; Babic, S; Luedtke, RR; Mach, RH Synthesis and characterization of selective dopamine D2 receptor antagonists. 2. Azaindole, benzofuran, and benzothiophene analogs of L-741,626. Bioorg Med Chem 18:5291-300 (2010) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50322245
Synonyms:
1-((1H-Pyrrolo[2,3-b]pyridine-3-yl)methyl)-4-(4-iodophenyl)piperidin-4-ol oxalate | CHEMBL1172208
Type:
Small organic molecule
Emp. Form.:
C19H20IN3O
Mol. Mass.:
433.2861
SMILES:
OC1(CCN(Cc2c[nH]c3ncccc23)CC1)c1ccc(I)cc1
Structure:
Search PDB for entries with ligand similarity: