Reaction Details Report a problem with these data
Target
Pancreatic triacylglycerol lipase
Ligand
BDBM50380997
Substrate
n/a
Meas. Tech.
ChEMBL_814113 (CHEMBL2020707)
IC50
75400±n/a nM
Citation
 Ahn, JH; Liu, Q; Lee, C; Ahn, MJ; Yoo, HS; Hwang, BY; Lee, MK A new pancreatic lipase inhibitor from Broussonetia kanzinoki. Bioorg Med Chem Lett 22:2760-3 (2012) [PubMed]  Article 
Target
Name:
Pancreatic triacylglycerol lipase
Synonyms:
LIPP_PIG | PL | PNLIP | PTL | Pancreatic lipase | Pancreatic triacylglycerol lipase
Type:
Enzyme
Mol. Mass.:
50080.69
Organism:
Sus scrofa (Pig)
Description:
P00591
Residue:
450
Sequence:
SEVCFPRLGCFSDDAPWAGIVQRPLKILPWSPKDVDTRFLLYTNQNQNNYQELVADPSTITNSNFRMDRKTRFIIHGFIDKGEEDWLSNICKNLFKVESVNCICVDWKGGSRTGYTQASQNIRIVGAEVAYFVEVLKSSLGYSPSNVHVIGHSLGSHAAGEAGRRTNGTIERITGLDPAEPCFQGTPELVRLDPSDAKFVDVIHTDAAPIIPNLGFGMSQTVGHLDFFPNGGKQMPGCQKNILSQIVDIDGIWEGTRDFVACNHLRSYKYYADSILNPDGFAGFPCDSYNVFTANKCFPCPSEGCPQMGHYADRFPGKTNGVSQVFYLNTGDASNFARWRYKVSVTLSGKKVTGHILVSLFGNEGNSRQYEIYKGTLQPDNTHSDEFDSDVEVGDLQKVKFIWYNNNVINPTLPRVGASKITVERNDGKVYDFCSQETVREEVLLTLNPC
  
Inhibitor
Name:
BDBM50380997
Synonyms:
BROUSSONIN B
Type:
Small organic molecule
Emp. Form.:
C16H18O3
Mol. Mass.:
258.3123
SMILES:
COc1cc(O)ccc1CCCc1ccc(O)cc1
Structure:
Search PDB for entries with ligand similarity: