Reaction Details Report a problem with these data
Target
Somatostatin receptor type 3
Ligand
BDBM50389589
Substrate
n/a
Meas. Tech.
ChEMBL_833945 (CHEMBL2072631)
Kd
2±n/a nM
Citation
 Pasternak, A; Feng, Z; de Jesus, R; Ye, Z; He, S; Dobbelaar, P; Bradley, SA; Chicchi, GG; Tsao, KL; Trusca, D; Eiermann, GJ; Li, C; Feng, Y; Wu, M; Shao, Q; Zhang, BB; Nargund, R; Mills, SG; Howard, AD; Yang, L; Zhou, YP Stimulation of Glucose-Dependent Insulin Secretion by a Potent, Selective sst3 Antagonist. ACS Med Chem Lett 3:289-293 (2012) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 3
Synonyms:
SOMATOSTATIN SST3 | SS-3-R | SS3-R | SS3R | SSR-28 | SSR3_HUMAN | SSTR3 | Somatostatin receptor type 3 (SSTR3)
Type:
Protein
Mol. Mass.:
45855.97
Organism:
Homo sapiens (Human)
Description:
P32745
Residue:
418
Sequence:
MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL
  
Inhibitor
Name:
BDBM50389589
Synonyms:
CHEMBL2069501
Type:
Small organic molecule
Emp. Form.:
C26H30N4O2
Mol. Mass.:
430.542
SMILES:
CCOCC1(COCC)N[C@H](Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1 |r|
Structure:
Search PDB for entries with ligand similarity: