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Target
C-X-C chemokine receptor type 3
Ligand
BDBM50400943
Substrate
n/a
Meas. Tech.
ChEMBL_880272 (CHEMBL2215850)
Ki
>316.23±n/a nM
Citation
 Wijtmans, M; Verzijl, D; Bergmans, S; Lai, M; Bosch, L; Smit, MJ; de Esch, IJ; Leurs, R CXCR3 antagonists: quaternary ammonium salts equipped with biphenyl- and polycycloaliphatic-anchors. Bioorg Med Chem 19:3384-93 (2011) [PubMed]  Article 
Target
Name:
C-X-C chemokine receptor type 3
Synonyms:
AAO92295.1 | C-X-C chemokine receptor type 3 | C-X-C chemokine receptor type 3 (CXCR3) | C-X-C chemokine receptor type 3 (CXCR3A) | CXCR3 | CXCR3A | CXCR3_HUMAN | GPR9 | chemokine (C-X-C motif) receptor 3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40665.65
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
368
Sequence:
MVLEVSDHQVLNDAEVAALLENFSSSYDYGENESDSCCTSPPCPQDFSLNFDRAFLPALYSLLFLLGLLGNGAVAAVLLSRRTALSSTDTFLLHLAVADTLLVLTLPLWAVDAAVQWVFGSGLCKVAGALFNINFYAGALLLACISFDRYLNIVHATQLYRRGPPARVTLTCLAVWGLCLLFALPDFIFLSAHHDERLNATHCQYNFPQVGRTALRVLQLVAGFLLPLLVMAYCYAHILAVLLVSRGQRRLRAMRLVVVVVVAFALCWTPYHLVVLVDILMDLGALARNCGRESRVDVAKSVTSGLGYMHCCLNPLLYAFVGVKFRERMWMLLLRLGCPNQRGLQRQPSSSRRDSSWSETSEASYSGL
  
Inhibitor
Name:
BDBM50400943
Synonyms:
CHEMBL2205086
Type:
Small organic molecule
Emp. Form.:
C26H31NO2
Mol. Mass.:
389.5298
SMILES:
COC(=O)c1cccc(c1)-c1ccc(CN(C)CC2=CC[C@H]3C[C@@H]2C3(C)C)cc1 |r,t:19,TLB:17:18:22:24|
Structure:
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