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Target
Histidine-rich protein PFHRP-II
Ligand
BDBM50134484
Substrate
n/a
Meas. Tech.
ChEBML_155132
IC50
>200000±n/a nM
Citation
 Ryckebusch, A; Deprez-Poulain, R; Debreu-Fontaine, MA; Vandaele, R; Mouray, E; Grellier, P; Sergheraert, C Synthesis and antimalarial evaluation of new 1,4-bis(3-aminopropyl)piperazine derivatives. Bioorg Med Chem Lett 13:3783-7 (2003) [PubMed]  Article 
Target
Name:
Histidine-rich protein PFHRP-II
Synonyms:
HRP1_PLAFA | Histidine-rich protein | Histidine-rich protein PFHRP-II
Type:
PROTEIN
Mol. Mass.:
35156.49
Organism:
Plasmodium falciparum
Description:
ChEMBL_500704
Residue:
332
Sequence:
MVSFSKNKVLSAAVFASVLLLDNNNSAFNNNLCSKNAKGLNLNKRLLHETQAHVDDAHHAHHVADAHHAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHAAYAHHAHHASDAHHAADAHHAAYAHHAHHAADAHHAADAHHAAYAHHAHHAADAHHAADAHHATDAHHAHHAADAHHATDAHHAADAHHAADAHHATDAHHAADAHHATDAHHAADAHHAADAHHATDSHHAHHAADAHHAAAHHATDAHHAAAHHATDAHHAAAHHEAATHCLRH
  
Inhibitor
Name:
BDBM50134484
Synonyms:
CHEMBL122346 | N-{3-[4-(3-Diisobutylamino-propyl)-piperazin-1-yl]-propyl}-4-methoxy-benzamide
Type:
Small organic molecule
Emp. Form.:
C26H46N4O2
Mol. Mass.:
446.669
SMILES:
COc1ccc(cc1)C(=O)NCCCN1CCN(CCCN(CC(C)C)CC(C)C)CC1
Structure:
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