Reaction Details Report a problem with these data
Target
Arabinose 5-phosphate isomerase KdsD
Ligand
BDBM50405129
Substrate
n/a
Meas. Tech.
ChEMBL_36028 (CHEMBL646429)
IC50
8700000±n/a nM
Citation
 Bigham, EC; Gragg, CE; Hall, WR; Kelsey, JE; Mallory, WR; Richardson, DC; Benedict, C; Ray, PH Inhibition of arabinose 5-phosphate isomerase. An approach to the inhibition of bacterial lipopolysaccharide biosynthesis. J Med Chem 27:717-26 (1984) [PubMed]  Article 
Target
Name:
Arabinose 5-phosphate isomerase KdsD
Synonyms:
Arabinose 5-phosphate isomerase | KDSD_SALTY | kdsD
Type:
PROTEIN
Mol. Mass.:
35000.37
Organism:
Salmonella typhimurium
Description:
ChEMBL_36028
Residue:
328
Sequence:
MSHLALQPGFDFQQAGKEVLEIEREGLAELDQYINQHFTLACEKMFNCTGKVVVMGMGKSGHIGRKMAATFASTGTSSFFVHPGEAAHGDLGMVTPQDVVIAISNSGESSEIAALIPVLKRLHVPLICITGRPESSMARAADVHLCVKVPKEACPLGLAPTSSTTATLVMGDALAVALLKARGFTAEDFALSHPGGALGRKLLLRVSDIMHTGDEIPHVNKHATLRDALLEITRKNLGMTVICDESMKIDGIFTDGDLRRVFDMGGDMRQLGIAEVMTPGGIRVRPGILAVDALNLMQSRHITSVLVADGDQLLGVLHMHDLLRAGVV
  
Inhibitor
Name:
BDBM50405129
Synonyms:
CHEMBL1161478
Type:
Small organic molecule
Emp. Form.:
C5H12NO8P
Mol. Mass.:
245.1244
SMILES:
ONCC(O)C(O)C(=O)COP(O)(O)=O
Structure:
Search PDB for entries with ligand similarity: