Reaction Details Report a problem with these data
Target
Cyclin-dependent kinase inhibitor 1
Ligand
BDBM50410020
Substrate
n/a
Meas. Tech.
ChEMBL_312419 (CHEMBL832970)
IC50
>20000±n/a nM
Citation
Wang, YD; Johnson, S; Powell, D; McGinnis, JP; Miranda, M; Rabindran, SK Inhibition of tumor cell proliferation by thieno[2,3-d]pyrimidin-4(1H)-one-based analogs. Bioorg Med Chem Lett 15:3763-6 (2005) [PubMed] Article
More Info.:
Target
Name:
Cyclin-dependent kinase inhibitor 1
Synonyms:
CAP20 | CDK-interacting protein 1 | CDKN1 | CDKN1A | CDN1A_HUMAN | CIP1 | MDA6 | PIC1 | SDI1 | WAF1
Type:
PROTEIN
Mol. Mass.:
18123.15
Organism:
Homo sapiens (Human)
Description:
ChEMBL_312386
Residue:
164
Sequence:
MSEPAGDVRQNPCGSKACRRLFGPVDSEQLSRDCDALMAGCIQEARERWNFDFVTETPLEGDFAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSCTLVPRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP