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Target
Alpha-1B adrenergic receptor
Ligand
BDBM50415772
Substrate
n/a
Meas. Tech.
ChEMBL_615773 (CHEMBL1100127)
Ki
53.7±n/a nM
Citation
 Franchini, S; Prandi, A; Sorbi, C; Tait, A; Baraldi, A; Angeli, P; Buccioni, M; Cilia, A; Poggesi, E; Fossa, P; Brasili, L Discovery of a new series of 5-HT1A receptor agonists. Bioorg Med Chem Lett 20:2017-20 (2010) [PubMed]  Article 
Target
Name:
Alpha-1B adrenergic receptor
Synonyms:
ADA1B_HUMAN | ADRA1B | Adrenergic alpha1B | Adrenergic receptor | Adrenergic receptor alpha | Alpha 1B-adrenoceptor | Alpha 1B-adrenoreceptor | Alpha-1B adrenergic receptor
Type:
Enzyme
Mol. Mass.:
56862.13
Organism:
Homo sapiens (Human)
Description:
P35368
Residue:
520
Sequence:
MNPDLDTGHNTSAPAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAIVGNILVILSVACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFVRILGCQCRGRGRRRRRRRRRLGGCAYTYRPWTRGGSLERSQSRKDSLDDSGSCLSGSQRTLPSASPSPGYLGRGAPPPVELCAFPEWKAPGALLSLPAPEPPGRRGRHDSGPLFTFKLLTEPESPGTDGGASNGGCEAAADVANGQPGFKSNMPLAPGQF
  
Inhibitor
Name:
BDBM50415772
Synonyms:
CHEMBL1078953
Type:
Small organic molecule
Emp. Form.:
C26H29NO4
Mol. Mass.:
419.5128
SMILES:
CCOc1ccccc1OCCNCC1COC(O1)(c1ccccc1)c1ccccc1
Structure:
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