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Target
Peptide deformylase
Ligand
BDBM50416424
Substrate
n/a
Meas. Tech.
ChEMBL_643979 (CHEMBL1211878)
IC50
11±n/a nM
Citation
 Lee, SK; Choi, KH; Lee, SJ; Suh, SW; Kim, BM; Lee, BJ Peptide deformylase inhibitors with retro-amide scaffold: synthesis and structure-activity relationships. Bioorg Med Chem Lett 20:4317-9 (2010) [PubMed]  Article 
Target
Name:
Peptide deformylase
Synonyms:
DEF_PSEAE | PDF | Polypeptide deformylase | def
Type:
PROTEIN
Mol. Mass.:
19357.88
Organism:
Pseudomonas aeruginosa
Description:
ChEMBL_643979
Residue:
168
Sequence:
MAILNILEFPDPRLRTIAKPVEVVDDAVRQLIDDMFETMYEAPGIGLAATQVNVHKRIVVMDLSEDKSEPRVFINPEFEPLTEDMDQYQEGCLSVPGFYENVDRPQKVRIKALDRDGNPFEEVAEGLLAVCIQHECDHLNGKLFVDYLSTLKRDRIRKKLEKQHRQQA
  
Inhibitor
Name:
BDBM50416424
Synonyms:
CHEMBL1208984
Type:
Small organic molecule
Emp. Form.:
C22H33N3O5
Mol. Mass.:
419.5145
SMILES:
COc1ccccc1C(=O)N[C@H](C(=O)N(CC1CCCC1)CC(=O)NO)C(C)(C)C |r|
Structure:
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