Reaction Details Report a problem with these data
Target
D(2) dopamine receptor
Ligand
BDBM50416715
Substrate
n/a
Meas. Tech.
ChEMBL_652495 (CHEMBL1225698)
Ki
100±n/a nM
Citation
 Micheli, F; Hamprecht, D; Bonanomi, G; Di Fabio, R; Donati, D; Gentile, G; Heidbreder, C; Prandi, A; Tarsi, L; Terreni, S [3-azabicyclo[3.1.0]hex-1-yl]phenyl-benzenesulfonamides as selective dopamine D3 antagonists. Bioorg Med Chem Lett 20:5491-4 (2010) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50416715
Synonyms:
CHEMBL1224697
Type:
Small organic molecule
Emp. Form.:
C22H28N2O2S
Mol. Mass.:
384.535
SMILES:
CCN1C[C@H]2C[C@]2(C1)c1ccc(NS(=O)(=O)c2ccc(cc2)C(C)C)cc1 |r|
Structure:
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