Reaction Details Report a problem with these data
Target
Cytochrome P450 2B1
Ligand
BDBM50027787
Substrate
n/a
Meas. Tech.
ChEMBL_774165 (CHEMBL1908260)
Ki
5200±n/a nM
Citation
 Fontana, E; Dansette, PM; Poli, SM Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity. Curr Drug Metab 6:413-54 (2005) [PubMed]  Article 
Target
Name:
Cytochrome P450 2B1
Synonyms:
CP2B1_RAT | Cyp2b-1 | Cyp2b1
Type:
PROTEIN
Mol. Mass.:
55940.51
Organism:
Rattus norvegicus
Description:
ChEMBL_774167
Residue:
491
Sequence:
MEPTILLLLALLVGFLLLLVRGHPKSRGNFPPGPRPLPLLGNLLQLDRGGLLNSFMQLREKYGDVFTVHLGPRPVVMLCGTDTIKEALVGQAEDFSGRGTIAVIEPIFKEYGVIFANGERWKALRRFSLATMRDFGMGKRSVEERIQEEAQCLVEELRKSQGAPLDPTFLFQCITANIICSIVFGERFDYTDRQFLRLLELFYRTFSLLSSFSSQVFEFFSGFLKYFPGAHRQISKNLQEILDYIGHIVEKHRATLDPSAPRDFIDTYLLRMEKEKSNHHTEFHHENLMISLLSLFFAGTETSSTTLRYGFLLMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRSKMPYTDAVIHEIQRFSDLVPIGVPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPQYFDHPDSFNPEHFLDANGALKKSEAFMPFSTGKRICLGEGIARNELFLFFTTILQNFSVSSHLAPKDIDLTPKESGIGKIPPTYQICFSAR
  
Inhibitor
Name:
BDBM50027787
Synonyms:
CHEMBL1908211 | N-Methylcarbazole
Type:
Small organic molecule
Emp. Form.:
C13H11N
Mol. Mass.:
181.2331
SMILES:
Cn1c2ccccc2c2ccccc12
Structure:
Search PDB for entries with ligand similarity: