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Target
Solute carrier organic anion transporter family member 1A4
Ligand
BDBM50420193
Substrate
n/a
Meas. Tech.
ChEMBL_838982 (CHEMBL2078499)
Ki
37000±n/a nM
Citation
 Gao, B; Wenzel, A; Grimm, C; Vavricka, SR; Benke, D; Meier, PJ; Remè, CE Localization of organic anion transport protein 2 in the apical region of rat retinal pigment epithelium. Invest Ophthalmol Vis Sci 43:510-4 (2002) [PubMed] 
Target
Name:
Solute carrier organic anion transporter family member 1A4
Synonyms:
Brain digoxin carrier protein | Brain-specific organic anion transporter | OATP-B1 | Oatp1a4 | Oatp2 | SO1A4_RAT | Slc21a5 | Slco1a4 | Sodium-independent organic anion-transporting polypeptide 2 | Solute carrier family 21 member 5
Type:
PROTEIN
Mol. Mass.:
73261.82
Organism:
Rattus norvegicus
Description:
ChEMBL_836631
Residue:
661
Sequence:
MGKSEKRVATHGVRCFAKIKMFLLALTCAYVSKSLSGTYMNSMLTQIERQFGIPTSIVGLINGSFEIGNLLLIIFVSYFGTKLHRPIMIGVGCAVMGLGCFLISLPHFLMGQYEYETILPTSNVSSNSFFCVENRSQTLNPTQDPSECVKEMKSLMWIYVLVGNIIRGIGETPIMPLGISYIEDFAKSENSPLYIGILETGMTIGPLIGLLLASSCANIYVDIESVNTDDLTITPTDTRWVGAWWIGFLVCAGVNILTSFPFFFFPKTLPKEGLQENVDGTENAKEKKHRKKAKEEKRGITKDFFVFMKSLSCNPIYMLFILISVLQFNAFINSFTFMPKYLEQQYGKSTAEVVFLMGLYMLPPICLGYLIGGLIMKKFKVTVKKAAHLAFWLCLSEYLLSFLSYVMTCDNFPVAGLTTSYEGVQHQLYVENKVLADCNTRCNCSTNTWDPVCGDNGLAYMSACLAGCEKSVGTGTNMVFQNCSCIQSSGNSSAVLGLCNKGPDCANKLQYFLIIAIFGCFIYSLAGIPGYMVLLRCIKSEEKSLGVGLHAFCIRILAGIPAPIYFGALIDRTCLHWGTLKCGEPGACRMYDINSFRRLYLGLPAALRGASFVPAFFILRLTRTFQFPGDIESSKTDHAEMKLTLKESECTEVLRSKVTED
  
Inhibitor
Name:
BDBM50420193
Synonyms:
CHEMBL2074656
Type:
Small organic molecule
Emp. Form.:
C42H58NO
Mol. Mass.:
592.9155
SMILES:
C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/c1cc(\C=C\C=C(/C)\C=C\C2=C(C)CCCC2(C)C)cc[n+]1CCO |c:4,30|
Structure:
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