Reaction Details Report a problem with these data
Target
P2Y purinoceptor 1
Ligand
BDBM50436899
Substrate
n/a
Meas. Tech.
ChEMBL_971691 (CHEMBL2404230)
Ki
12±n/a nM
Citation
 Pi, Z; Sutton, J; Lloyd, J; Hua, J; Price, L; Wu, Q; Chang, M; Zheng, J; Rehfuss, R; Huang, CS; Wexler, RR; Lam, PY 2-Aminothiazole based P2Y(1) antagonists as novel antiplatelet agents. Bioorg Med Chem Lett 23:4206-9 (2013) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 1
Synonyms:
ATP receptor | P2RY1 | P2RY1_HUMAN | P2Y purinoceptor 1 (P2Y1) | P2Y1 | Purinergic receptor | Purinergic receptor P2Y1
Type:
Enzyme
Mol. Mass.:
42090.25
Organism:
Homo sapiens (Human)
Description:
P47900
Residue:
373
Sequence:
MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVVVAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLIVRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLNILPEFKQNGDTSL
  
Inhibitor
Name:
BDBM50436899
Synonyms:
CHEMBL2401864
Type:
Small organic molecule
Emp. Form.:
C32H37F3N4O2S
Mol. Mass.:
598.722
SMILES:
CN(C)CC(C)(C)COc1cccc(c1)-c1sc(Nc2cccnc2Oc2ccccc2C(C)(C)C)nc1C(F)(F)F
Structure:
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