Reaction Details Report a problem with these data
Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50336571
Substrate
n/a
Meas. Tech.
ChEMBL_1334692 (CHEMBL3238575)
Ki
20±n/a nM
Citation
 Mach, RH; Zeng, C; Hawkins, WG Thes2 receptor: a novel protein for the imaging and treatment of cancer. J Med Chem 56:7137-60 (2013) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein
Type:
Protein
Mol. Mass.:
25307.17
Organism:
Cavia porcellus (Guinea pig)
Description:
Q60492
Residue:
223
Sequence:
MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSKLIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50336571
Synonyms:
(+)-(R)-N-[(5-Methoxy-1,2,3,4-tetrahydronaphthalen)-1-yl]-2-(4-cyclohexylpiperazine-1-yl)acetamide | CHEMBL1672031
Type:
Small organic molecule
Emp. Form.:
C23H35N3O2
Mol. Mass.:
385.5429
SMILES:
COc1cccc2[C@@H](CCCc12)NC(=O)CN1CCN(CC1)C1CCCCC1 |r|
Structure:
Search PDB for entries with ligand similarity: