Reaction Details Report a problem with these data
Target
Dipeptidyl carboxypeptidase
Ligand
BDBM50010477
Substrate
n/a
Meas. Tech.
ChEMBL_1353482 (CHEMBL3269465)
IC50
150000±n/a nM
Citation
 Kramer, GJ; Mohd, A; Schwager, SL; Masuyer, G; Acharya, KR; Sturrock, ED; Bachmann, BO Interkingdom pharmacology of Angiotensin-I converting enzyme inhibitor phosphonates produced by actinomycetes. ACS Med Chem Lett 5:346-51 (2014) [PubMed]  Article 
Target
Name:
Dipeptidyl carboxypeptidase
Synonyms:
DCP_ECOLI | Dipeptidyl carboxypeptidase | JW1531 | Peptidyl-dipeptidase dcp | dcp
Type:
PROTEIN
Mol. Mass.:
77504.73
Organism:
Escherichia coli (strain K12)
Description:
ChEMBL_108355
Residue:
681
Sequence:
MTTMNPFLVQSTLPYLAPHFDQIANHHYRPAFDEGMQQKRAEIAAIALNPQMPDFNNTILALEQSGELLTRVTSVFFAMTAAHTNDELQRLDEQFSAELAELANDIYLNGELFARVDAVWQRRESLGLDSESIRLVEVIHQRFVLAGAKLAQADKAKLKVLNTEAATLTSQFNQRLLAANKSGGLVVNDIAQLAGMSEQEIALAAEAAREKGLDNKWLIPLLNTTQQPALAEMRDRATREKLFIAGWTRAEKNDANDTRAIIQRLVEIRAQQATLLGFPHYAAWKIADQMAKTPEAALNFMREIVPAARQRASDELASIQAVIDKQQGGFSAQPWDWAFYAEQVRREKFDLDEAQLKPYFELNTVLNEGVFWTANQLFGIKFVERFDIPVYHPDVRVWEIFDHNGVGLALFYGDFFARDSKSGGAWMGNFVEQSTLNKTHPVIYNVCNYQKPAAGEPALLLWDDVITLFHEFGHTLHGLFARQRYATLSGTNTPRDFVEFPSQINEHWATHPQVFARYARHYQSGAAMPDELQQKMRNASLFNKGYEMSELLSAALLDMRWHCLEENEAMQDVDDFELRALVAENMDLPAIPPRYRSSYFAHIFGGGYAAGYYAYLWTQMLADDGYQWFVEQGGLTRENGLRFREAILSRGNSEDLERLYRQWRGKAPKIMPMLQHRGLNI
  
Inhibitor
Name:
BDBM50010477
Synonyms:
CHEMBL1233799
Type:
Small organic molecule
Emp. Form.:
C25H34N3O8P
Mol. Mass.:
535.5265
SMILES:
CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)P(O)(O)=O |r|
Structure:
Search PDB for entries with ligand similarity: