Reaction Details Report a problem with these data
Target
Melatonin receptor type 1B
Ligand
BDBM50240440
Substrate
n/a
Meas. Tech.
ChEMBL_1352245 (CHEMBL3268963)
Ki
1.5±n/a nM
Citation
 Zlotos, DP; Jockers, R; Cecon, E; Rivara, S; Witt-Enderby, PA MT1 and MT2 melatonin receptors: ligands, models, oligomers, and therapeutic potential. J Med Chem 57:3161-85 (2014) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1B
Synonyms:
MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:
Enzyme
Mol. Mass.:
40203.54
Organism:
Homo sapiens (Human)
Description:
P49286
Residue:
362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQADAL
  
Inhibitor
Name:
BDBM50240440
Synonyms:
4-P-PDOT | CHEMBL285718 | N-(4-Phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propionamide | N-(4-phenyl-1,2,3,4-tetrahydronaphthalen-2-yl)propionamide
Type:
Small organic molecule
Emp. Form.:
C19H21NO
Mol. Mass.:
279.3761
SMILES:
CCC(=O)NC1CC(c2ccccc2)c2ccccc2C1
Structure:
Search PDB for entries with ligand similarity: