Affinity DataKi: 0.00100nMAssay Description:Displacement of 2-[125I]Iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Displacement of [125I]2-iodomelatonin from MT2 receptor (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Displacement of [125I]2-iodomelatonin from human recombinant MT2 receptor expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University In Cairo
Curated by ChEMBL
The German University In Cairo
Curated by ChEMBL
Affinity DataKi: 0.0680nMAssay Description:Displacement of [125I]2-iodomelatonin from human recombinant MT1 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University In Cairo
Curated by ChEMBL
The German University In Cairo
Curated by ChEMBL
Affinity DataKi: 0.0800nMAssay Description:Inhibition of the 2-[125I]- iodomelatonin binding to Melatonin receptor type 1A expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University In Cairo
Curated by ChEMBL
The German University In Cairo
Curated by ChEMBL
Affinity DataKi: 0.0800nMAssay Description:Displacement of 2-[125I]-Iodomelatonin from human Melatonin receptor type 1A expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University In Cairo
Curated by ChEMBL
The German University In Cairo
Curated by ChEMBL
Affinity DataKi: 0.0990nMAssay Description:Displacement of 2-[125I]-Iodomelatonin from human Melatonin receptor type 1A expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University In Cairo
Curated by ChEMBL
The German University In Cairo
Curated by ChEMBL
Affinity DataKi: 0.0990nMAssay Description:Inhibition of the 2-[125I]- iodomelatonin binding to Melatonin receptor type 1A expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.110nMAssay Description:Displacement of 2-[125I]Iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.110nMAssay Description:Displacement of [125I]2-iodomelatonin from MT2 receptor (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Inhibition of the 2-[125I]- iodomelatonin binding to Melatonin receptor type 1B expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University In Cairo
Curated by ChEMBL
The German University In Cairo
Curated by ChEMBL
Affinity DataKi: 0.130nMAssay Description:Binding affinity of the compound against human Melatonin receptor type 1A by displacement of [125I]-iodomelatonin stably expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Compound was tested for binding affinity against human Melatonin receptor type 1B in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Displacement of 2-[125I]Iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University In Cairo
Curated by ChEMBL
The German University In Cairo
Curated by ChEMBL
Affinity DataKi: 0.180nMAssay Description:Agonist activity at MT1 receptor (unknown origin) expressed in mouse NIH3T3 cells assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [125I]2-iodomelatonin from human recombinant MT2 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University In Cairo
Curated by ChEMBL
The German University In Cairo
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of 2-[125I]-Iodomelatonin from human Melatonin receptor type 1A expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Displacement of [125I]2-iodomelatonin from human recombinant MT2 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.230nMAssay Description:Binding affinity of the compound against human Melatonin receptor type 1B by displacement of [125I]-iodomelatonin stably expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Displacement of [125I]2-iodomelatonin from human recombinant MT2 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Displacement of 2-[125I]Iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.290nMAssay Description:Inhibition of 2-[125I]-Iodomelatonin binding to human Melatonin receptor type 1B expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.290nMAssay Description:Agonist activity at MT2 receptor (unknown origin) expressed in mouse NIH3T3 cells assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University In Cairo
Curated by ChEMBL
The German University In Cairo
Curated by ChEMBL
Affinity DataKi: 0.304nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cell lysates after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Displacement of [125I]2-iodomelatonin from MT2 receptor (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Inhibition of the 2-[125I]- iodomelatonin binding to Melatonin receptor type 1B expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Inhibition of 2-[125I]-Iodomelatonin binding to human Melatonin receptor type 1B expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University In Cairo
Curated by ChEMBL
The German University In Cairo
Curated by ChEMBL
Affinity DataKi: 0.390nMAssay Description:Displacement of 2-[125I]-Iodomelatonin from human Melatonin receptor type 1A expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.410nMAssay Description:Binding affinity of the compound against human Melatonin receptor type 1B by displacement of [125I]-iodomelatonin stably expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.460nMAssay Description:Displacement of 2-[125I]Iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Displacement of 2-[125I]Iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University In Cairo
Curated by ChEMBL
The German University In Cairo
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Binding affinity to MT1 receptor (unknown origin) expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Displacement of [125I]2-iodomelatonin from human recombinant MT2 receptor expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University In Cairo
Curated by ChEMBL
The German University In Cairo
Curated by ChEMBL
Affinity DataKi: 0.525nMAssay Description:Displacement of 2-[125I]iodomelatonin from human melatonin MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Agonist activity at MT2 receptor (unknown origin) expressed in HEK293 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University In Cairo
Curated by ChEMBL
The German University In Cairo
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Binding affinity to MT1 receptor (unknown origin) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University In Cairo
Curated by ChEMBL
The German University In Cairo
Curated by ChEMBL
Affinity DataKi: 0.630nMAssay Description:Displacement of [125I]2-iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.741nMAssay Description:Displacement of 2-[125I]iodomelatonin from human melatonin MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Displacement of [125I]2-iodomelatonin from human recombinant MT2 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of 2-[125I]Iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.960nMAssay Description:Binding affinity of the compound against human Melatonin receptor type 1B by displacement of [125I]-iodomelatonin stably expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of 2-[125I]Iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of 2-[125I]-Iodomelatonin binding to human Melatonin receptor type 1B expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of 2-[125I]-Iodomelatonin binding to human Melatonin receptor type 1B expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University In Cairo
Curated by ChEMBL
The German University In Cairo
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity to MT1 receptor (unknown origin) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University In Cairo
Curated by ChEMBL
The German University In Cairo
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Agonist activity at MT1 receptor (unknown origin) expressed in mouse NIH3T3 cells assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Antagonist activity at MT2 receptor (unknown origin) expressed in mouse NIH3T3 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of 2-[125I]-Iodomelatonin binding to human Melatonin receptor type 1B expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University In Cairo
Curated by ChEMBL
The German University In Cairo
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [125I]2-iodomelatonin from MT1 receptor (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University In Cairo
Curated by ChEMBL
The German University In Cairo
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [125I]2-iodomelatonin from human recombinant MT1 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair