Reaction Details Report a problem with these data
Target
Melatonin receptor type 1B
Ligand
BDBM50011344
Substrate
n/a
Meas. Tech.
ChEMBL_1352252 (CHEMBL3268970)
Ki
0.290000±n/a nM
Citation
 Zlotos, DP; Jockers, R; Cecon, E; Rivara, S; Witt-Enderby, PA MT1 and MT2 melatonin receptors: ligands, models, oligomers, and therapeutic potential. J Med Chem 57:3161-85 (2014) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1B
Synonyms:
MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:
Enzyme
Mol. Mass.:
40203.54
Organism:
Homo sapiens (Human)
Description:
P49286
Residue:
362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQADAL
  
Inhibitor
Name:
BDBM50011344
Synonyms:
CHEMBL3260982
Type:
Small organic molecule
Emp. Form.:
C18H22N2O4
Mol. Mass.:
330.3783
SMILES:
CCOC(=O)c1[nH]c2ccc(OC)c3CC[C@H](CNC(C)=O)c1c23 |r|
Structure:
Search PDB for entries with ligand similarity: