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Target
Glutathione S-transferase Mu 1
Ligand
BDBM50044547
Substrate
n/a
Meas. Tech.
ChEMBL_1454324 (CHEMBL3364164)
IC50
50±n/a nM
Citation
 Abet, V; Mariani, A; Truscott, FR; Britton, S; Rodriguez, R Biased and unbiased strategies to identify biologically active small molecules. Bioorg Med Chem 22:4474-89 (2014) [PubMed]  Article 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST 1-1 | GST class-mu 1 | GSTM1_MOUSE | Glutathione S-transferase GT8.7 | Glutathione S-transferase Mu 1 | Gstm1 | pmGT10
Type:
PROTEIN
Mol. Mass.:
25973.23
Organism:
Mus musculus
Description:
ChEMBL_12438
Residue:
218
Sequence:
MPMILGYWNVRGLTHPIRMLLEYTDSSYDEKRYTMGDAPDFDRSQWLNEKFKLGLDFPNLPYLIDGSHKITQSNAILRYLARKHHLDGETEEERIRADIVENQVMDTRMQLIMLCYNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYRMFEPKCLDAFPNLRDFLARFEGLKKISAYMKSSRYIATPIFSKMAHWSNK
  
Inhibitor
Name:
BDBM50044547
Synonyms:
CHEMBL3314090
Type:
Small organic molecule
Emp. Form.:
C48H56N14O20S2
Mol. Mass.:
1213.17
SMILES:
C[C@H](NC(=O)c1cccc(c1)C(=O)N[C@@H](C)C(=O)N\N=C\c1ccc(SC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O)c(c1)[N+]([O-])=O)C(=O)N\N=C\c1ccc(SC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O)c(c1)[N+]([O-])=O |r|
Structure:
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