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Target
Cyclin-dependent kinase 1
Ligand
BDBM27078
Substrate
n/a
Meas. Tech.
ChEMBL_1454338 (CHEMBL3364477)
IC50
52±n/a nM
Citation
 Abet, V; Mariani, A; Truscott, FR; Britton, S; Rodriguez, R Biased and unbiased strategies to identify biologically active small molecules. Bioorg Med Chem 22:4474-89 (2014) [PubMed]  Article 
Target
Name:
Cyclin-dependent kinase 1
Synonyms:
CDC2 | CDC28A | CDK1 | CDK1_HUMAN | CDKN1 | Cell division control protein 2 homolog | Cell division protein kinase 1 | Cyclin-dependent kinase 1 (CDK1) | P34CDC2 | p34 protein kinase
Type:
Enzyme Subunit
Mol. Mass.:
34101.08
Organism:
Homo sapiens (Human)
Description:
P06493
Residue:
297
Sequence:
MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM
  
Inhibitor
Name:
BDBM27078
Synonyms:
N-[3-(1H-1,3-benzodiazol-2-yl)-1H-pyrazol-4-yl]benzamide | pyrazole-benzimidazole amide analogue, 7
Type:
Small organic molecule
Emp. Form.:
C17H13N5O
Mol. Mass.:
303.318
SMILES:
O=C(Nc1c[nH]nc1-c1nc2ccccc2[nH]1)c1ccccc1
Structure:
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