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Target
Amine oxidase [flavin-containing] A
Ligand
BDBM50130936
Substrate
n/a
Meas. Tech.
ChEBML_1526078
IC50
35100±n/a nM
Citation
 Suthar, SK; Bansal, S; Alam, MM; Jaiswal, V; Tiwari, A; Chaudhary, A; Alex, AT; Joseph, A Design, synthesis, and biological evaluation of oxindole derivatives as antidepressive agents. Bioorg Med Chem Lett 25:5281-5 (2015) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] A
Synonyms:
AOFA_BOVIN | Amine oxidase [flavin-containing] A | MAO-A | MAOA | Monoamine Oxidase Type A (MAO-A) | Monoamine oxidase | Monoamine oxidase A | Monoamine oxidase type A
Type:
PROTEIN
Mol. Mass.:
59764.63
Organism:
Bos taurus
Description:
ChEMBL_1501477
Residue:
527
Sequence:
MESLQKTSDAGQMFDVVVIGGGISGLSAAKLLAEHEVNVLVLEARERVGGRTYTVRNEHVDYVDVGGAYVGPTQNRILRLSKQLGLETYKVNVNERLVHYVKGKTYPFRGAFPPVWNPIAYLDYNNLWRTMDNMGKEIPADAPWEAPHAVEWDKMTMKDLIEKICWTKTARQFASLFVNINVTSEPHEVSALWFLWYVKQCGGTTRIFSITNGGQERKFVGGSGQVSERIMQLLGDRVKLRSPVTYVDQSSENITVETLNRELYECRYVISAIPPTLTAKIHFRPELPSERNQLIQRLPMGAVIKCMMYYKEAFWKKKDYCGCMIIEDEEAPISITLDDTKPDGSLPAIMGFILARKADRLAKVHKDIRKRKICELYAKVLGSQEALHPVHYEEKNWCQEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALGKLSAKDIWIQEPEAEDVPAVEITPSFWERNLPSVSGLLKIVGFSTSITALWFVMYRFRLLSRS
  
Inhibitor
Name:
BDBM50130936
Synonyms:
CHEMBL3633204
Type:
Small organic molecule
Emp. Form.:
C13H8BrNOS
Mol. Mass.:
306.178
SMILES:
Brc1ccc(\C=C2/C(=O)Nc3ccccc23)s1
Structure:
Search PDB for entries with ligand similarity: