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Target
Alpha-1B adrenergic receptor
Ligand
BDBM50067212
Substrate
n/a
Meas. Tech.
ChEMBL_1620803 (CHEMBL3863086)
EC50
0.860000±n/a nM
Citation
 Rak, A; Canale, V; Marciniec, K; Zmudzki, P; Kotanska, M; Knutelska, J; Siwek, A; Stachowicz, G; Bednarski, M; Nowinski, L; Zygmunt, M; Zajdel, P; Sapa, J Arylsulfonamide derivatives of (aryloxy)ethyl pyrrolidines and piperidines asa Bioorg Med Chem 24:5582-5591 (2016) [PubMed]  Article 
Target
Name:
Alpha-1B adrenergic receptor
Synonyms:
ADA1B_HUMAN | ADRA1B | Adrenergic alpha1B | Adrenergic receptor | Adrenergic receptor alpha | Alpha 1B-adrenoceptor | Alpha 1B-adrenoreceptor | Alpha-1B adrenergic receptor
Type:
Enzyme
Mol. Mass.:
56862.13
Organism:
Homo sapiens (Human)
Description:
P35368
Residue:
520
Sequence:
MNPDLDTGHNTSAPAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAIVGNILVILSVACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFVRILGCQCRGRGRRRRRRRRRLGGCAYTYRPWTRGGSLERSQSRKDSLDDSGSCLSGSQRTLPSASPSPGYLGRGAPPPVELCAFPEWKAPGALLSLPAPEPPGRRGRHDSGPLFTFKLLTEPESPGTDGGASNGGCEAAADVANGQPGFKSNMPLAPGQF
  
Inhibitor
Name:
BDBM50067212
Synonyms:
CHEBI:8093 | Cyclomydril | Duo-Medihaler | Phenylephrine
Type:
Small organic molecule
Emp. Form.:
C9H13NO2
Mol. Mass.:
167.205
SMILES:
CNC[C@H](O)c1cccc(O)c1 |r|
Structure:
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