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Target
Mu-type opioid receptor
Ligand
BDBM50008234
Substrate
n/a
Meas. Tech.
ChEMBL_1643866 (CHEMBL3992795)
IC50
1330±n/a nM
Citation
 Chen, SR; Ke, YY; Yeh, TK; Lin, SY; Ou, LC; Chen, SC; Chang, WT; Chang, HF; Wu, ZH; Hsieh, CC; Law, PY; Loh, HH; Shih, C; Lai, YK; Yeh, SH; Ueng, SH Discovery, structure-activity relationship studies, and anti-nociceptive effects of N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamides as novel opioid receptor agonists. Eur J Med Chem 126:202-217 (2017) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50008234
Synonyms:
CHEMBL4093524
Type:
Small organic molecule
Emp. Form.:
C22H28N2O
Mol. Mass.:
336.4705
SMILES:
CCCCN1CCc2ccccc2C1CNC(=O)c1ccc(C)cc1
Structure:
Search PDB for entries with ligand similarity: