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Target
Trace amine-associated receptor 5
Ligand
BDBM50100977
Substrate
n/a
Meas. Tech.
ChEMBL_1643991 (CHEMBL3992920)
EC50
>10000±n/a nM
Citation
 Tonelli, M; Espinoza, S; Gainetdinov, RR; Cichero, E Novel biguanide-based derivatives scouted as TAAR1 agonists: Synthesis, biological evaluation, ADME prediction and molecular docking studies. Eur J Med Chem 127:781-792 (2017) [PubMed]  Article 
Target
Name:
Trace amine-associated receptor 5
Synonyms:
Gm227 | TAAR5_MOUSE | TaR-5 | Taar5 | Trace amine receptor 5 | Trace amine-associated receptor 5 | Trimethylamine receptor | mTaar5
Type:
PROTEIN
Mol. Mass.:
38230.08
Organism:
Mus musculus
Description:
ChEMBL_116770
Residue:
337
Sequence:
MRAVLLPGSGEQPTAFCYQVNGSCPRTVHPLAIQVVIYLACAVGVLITVLGNLFVVFAVSYFKVLHTPTNFLLLSLALADMLLGLLVLPLSTVRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPLLYPSKFTVRTALRYIVAGWGIPAAYTAFFLYTDVVERALSQWLEEMPCVGSCQLLFNKFWGWLNFPAFFVPCLIMISLYLKIFVVATRQAQQIRTLSQSLAGAVKRERKAAKTLGIAVGIYLVCWLPFTVDTLVDSLLNFITPPLVFDIFIWFAYFNSACNPIIYVFSYRWFRKALKLLLSREIFSPRTPTVDLYHD
  
Inhibitor
Name:
BDBM50100977
Synonyms:
3,4-dichloro-phenylbiguanide | CHEMBL41433 | N-(3,4-dichlorophenyl)imidodicarbonimidic diamide
Type:
Small organic molecule
Emp. Form.:
C8H9Cl2N5
Mol. Mass.:
246.097
SMILES:
NC(=N)N=C(N)Nc1ccc(Cl)c(Cl)c1 |w:3.2|
Structure:
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