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Target
Serine/threonine-protein kinase pim-3
Ligand
BDBM50299246
Substrate
n/a
Meas. Tech.
Inhibition Assay
IC50
4.4e+2±n/a nM
Citation
 Anizon, F; Moreau, P; Prudhomme, M; Cohen, P; Aboab, B; Akue-Gedu, R; Rossignol, E Pyrrolo[2,3-a] carbazoles and use thereof as PIM kinase inhibitors US Patent  US8481586 Publication Date 7/9/2013 
Target
Name:
Serine/threonine-protein kinase pim-3
Synonyms:
PIM3 | PIM3_HUMAN | Serine/threonine-protein kinase pim-3 (PIM3)
Type:
Protein
Mol. Mass.:
35888.19
Organism:
Homo sapiens (Human)
Description:
Q86V86
Residue:
326
Sequence:
MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRIADGLPVAVKHVVKERVTEWGSLGGATVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFLLVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDLRSGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVCGDIPFEQDEEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWMLGADGGVPESCDLRLCTLDPDDVASTTSSSESL
  
Inhibitor
Name:
BDBM50299246
Synonyms:
7-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole | CHEMBL575336 | US8481586, 15
Type:
Small organic molecule
Emp. Form.:
C14H9BrN2
Mol. Mass.:
285.139
SMILES:
Brc1ccc2[nH]c3c(ccc4cc[nH]c34)c2c1
Structure:
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