Compile Data Set for Download or QSAR
maximum 50k data
Found 174 with Last Name = 'prudhomme' and Initial = 'm'
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50268249(12,13-[6-Deoxy-6-amino-4-O-methyl-D-mannopyranosyl...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of GST-tagged human full-length CHK1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50299249(1,10-Dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Pim-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50299249(1,10-Dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde...)
Affinity DataIC50:  10nMAssay Description:Inhibition assay using PIM-1, PIM-2 and PIM-3.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50216159(5-hydroxy-pyrrolo[3',4':5,6]indolizino[8,7-b]indol...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50220067(11H-2,5,11-triaza-benzo[a]trindene-1,3,4,6-tetraon...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50220067(11H-2,5,11-triaza-benzo[a]trindene-1,3,4,6-tetraon...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50220067(11H-2,5,11-triaza-benzo[a]trindene-1,3,4,6-tetraon...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human Chk1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50220064(4,7,11-trihydroxybenzo[a]pyrrolo[3,4-c]carbazole-1...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human Chk1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50376170(CHEMBL265446)
Affinity DataIC50:  24nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50216171(CHEMBL393545 | pyrrolo[3',4':5,6]indolizino[8,7-b]...)
Affinity DataIC50:  24nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50220072(11-hydroxybenzo[a]pyrrolo[3,4-c]carbazole-1,3,4,7(...)
Affinity DataIC50:  27nMAssay Description:Inhibition of human Chk1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50299245(7-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole-3-carb...)
Affinity DataIC50:  40nMAssay Description:Inhibition assay using PIM-1, PIM-2 and PIM-3.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50299245(7-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole-3-carb...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Pim-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50220066(6,7-dihydro-1H-cyclopenta[a]pyrrolo[3,4-c]carbazol...)
Affinity DataIC50:  43nMAssay Description:Inhibition of human Chk1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50236805(4,5-dihydro-11H-2,5,11-triaza-benzo[a]trindene-1,3...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50236805(4,5-dihydro-11H-2,5,11-triaza-benzo[a]trindene-1,3...)
Affinity DataIC50:  51nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50216161(5-bromo-pyrrolo[3',4':51,3-(2H,8H)-dione,6]indoliz...)
Affinity DataIC50:  66nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50216165(1,11-dihydro-1,3,5,11-tetraaza-benzo[a]trindene-4,...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50216165(1,11-dihydro-1,3,5,11-tetraaza-benzo[a]trindene-4,...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50216165(1,11-dihydro-1,3,5,11-tetraaza-benzo[a]trindene-4,...)
Affinity DataIC50:  81nMAssay Description:Inhibition of human Chk1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50216165(1,11-dihydro-1,3,5,11-tetraaza-benzo[a]trindene-4,...)
Affinity DataIC50:  81nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50216163(5-chloro-pyrrolo[3',4':5,6]indolizino[8,7-b]indole...)
Affinity DataIC50:  89nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50216157(11H-2,5,11,11b-Tetraaza-benzo[a]trindene-4,6-dione...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50220075(11-methylbenzo[a]pyrrolo[3,4-c]carbazole-1,3,4,7(2...)
Affinity DataIC50:  107nMAssay Description:Inhibition of human Chk1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50299249(1,10-Dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde...)
Affinity DataIC50:  120nMAssay Description:Inhibition of Pim-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50299249(1,10-Dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde...)
Affinity DataIC50:  120nMAssay Description:Inhibition assay using PIM-1, PIM-2 and PIM-3.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50220065(4,7-dihydroxy-11-methylbenzo[a]pyrrolo[3,4-c]carba...)
Affinity DataIC50:  161nMAssay Description:Inhibition of human Chk1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50299247(1-(1,10-Dihydropyrrolo[2,3-a]carbazol-3-yl)-2,2,2-...)
Affinity DataIC50:  170nMAssay Description:Inhibition assay using PIM-1, PIM-2 and PIM-3.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50299247(1-(1,10-Dihydropyrrolo[2,3-a]carbazol-3-yl)-2,2,2-...)
Affinity DataIC50:  170nMAssay Description:Inhibition of Pim-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50299250(7-(2,4-Difluorophenyl)-1,10-dihydropyrrolo[2,3-a]c...)
Affinity DataIC50:  200nMAssay Description:Inhibition of Pim-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50299250(7-(2,4-Difluorophenyl)-1,10-dihydropyrrolo[2,3-a]c...)
Affinity DataIC50:  200nMAssay Description:Inhibition assay using PIM-1, PIM-2 and PIM-3.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50299248(1,10-Dihydropyrrolo[2,3-a]carbazole-3-carboxamide ...)
Affinity DataIC50:  210nMAssay Description:Inhibition of Pim-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50299248(1,10-Dihydropyrrolo[2,3-a]carbazole-3-carboxamide ...)
Affinity DataIC50:  210nMAssay Description:Inhibition assay using PIM-1, PIM-2 and PIM-3.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50251213(6H-2-N-hydroxymethyl-5-ethoxycarbonyl-pyrrolo-[3,4...)
Affinity DataIC50:  210nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50220074(CHEMBL243930 | benzo[a]pyrrolo[3,4-c]carbazole-1,3...)
Affinity DataIC50:  269nMAssay Description:Inhibition of human Chk1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50220074(CHEMBL243930 | benzo[a]pyrrolo[3,4-c]carbazole-1,3...)
Affinity DataIC50:  269nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50220068(4,7-dihydroxybenzo[a]pyrrolo[3,4-c]carbazole-1,3(2...)
Affinity DataIC50:  311nMAssay Description:Inhibition of human Chk1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50220068(4,7-dihydroxybenzo[a]pyrrolo[3,4-c]carbazole-1,3(2...)
Affinity DataIC50:  311nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50216165(1,11-dihydro-1,3,5,11-tetraaza-benzo[a]trindene-4,...)
Affinity DataIC50:  350nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50251201(6,11-Dihydro-5H-2,5,11-triaza-benzo[a]trindene-1,3...)
Affinity DataIC50:  370nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50295872(5-Iodo-4-(1-Methyl-1H-indol-3-yl)pyrimidin-2-amine...)
Affinity DataIC50:  400nMAssay Description:Inhibition of rat recombinant DYRK1A expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50216157(11H-2,5,11,11b-Tetraaza-benzo[a]trindene-4,6-dione...)
Affinity DataIC50:  440nMAssay Description:Inhibition of human Chk1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50216157(11H-2,5,11,11b-Tetraaza-benzo[a]trindene-4,6-dione...)
Affinity DataIC50:  440nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50299246(7-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole | CHEM...)
Affinity DataIC50:  440nMAssay Description:Inhibition assay using PIM-1, PIM-2 and PIM-3.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50216157(11H-2,5,11,11b-Tetraaza-benzo[a]trindene-4,6-dione...)
Affinity DataIC50:  440nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50299246(7-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole | CHEM...)
Affinity DataIC50:  440nMAssay Description:Inhibition of Pim-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50299249(1,10-Dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde...)
Affinity DataIC50:  510nMAssay Description:Inhibition assay using PIM-1, PIM-2 and PIM-3.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50299249(1,10-Dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde...)
Affinity DataIC50:  510nMAssay Description:Inhibition of Pim-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50299245(7-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole-3-carb...)
Affinity DataIC50:  570nMAssay Description:Inhibition of Pim-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50299245(7-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole-3-carb...)
Affinity DataIC50:  570nMAssay Description:Inhibition assay using PIM-1, PIM-2 and PIM-3.More data for this Ligand-Target Pair
In DepthDetails US Patent
Displayed 1 to 50 (of 174 total ) | Next | Last >>
Jump to: