Reaction Details Report a problem with these data
Target
Cytidine deaminase
Ligand
BDBM159790
Substrate
n/a
Meas. Tech.
Enzymatic Assay
pH
7.4±n/a
IC50
101±n/a nM
Comments
extracted
Citation
 Belyakov, S; Duvall, B; Ferraris, D; Hamilton, G; Vaal, M Compositions and methods for treating cancer US Patent  US9040501 Publication Date 5/26/2015 
Target
Name:
Cytidine deaminase
Synonyms:
CDA | CDD | CDD_HUMAN | Cytidine deaminase | Cytidine deaminase (CDA)
Type:
Ezyme
Mol. Mass.:
16185.04
Organism:
Homo sapiens (Human)
Description:
P32320
Residue:
146
Sequence:
MAQKRPACTLKPECVQQLLVCSQEAKKSAYCPYSHFPVGAALLTQEGRIFKGCNIENACYPLGICAERTAIQKAVSEGYKDFRAIAIASDMQDDFISPCGACRQVMREFGTNWPVYMTKPDGTYIVMTVQELLPSSFGPEDLQKTQ
  
Inhibitor
Name:
BDBM159790
Synonyms:
US9040501, 876400
Type:
Small organic molecule
Emp. Form.:
C10H16N2O5
Mol. Mass.:
244.2444
SMILES:
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1CC=CCNC1=O |r,c:12|
Structure:
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