Reaction Details Report a problem with these data
Target
Forkhead box protein M1 [235-327]
Ligand
BDBM218821
Substrate
n/a
Meas. Tech.
Fluorescence-based Affinity Assay
Kd
1.7e+4±n/a nM
Citation
 Dong, C; Yan, P; Wang, J; Mu, H; Wang, S; Guo, F Rational identification of natural organic compounds to target the intermolecular interaction between Foxm and DNA in colorectal cancer. Bioorg Chem 70:12-16 (2017) [PubMed]  Article 
Target
Name:
Forkhead box protein M1 [235-327]
Synonyms:
FKHL16 | FOXM1 | FOXM1_HUMAN | Forkhead box M DNA-binding domain (Foxm DBD) | HFH11 | MPP2 | WIN
Type:
Protein
Mol. Mass.:
11168.28
Organism:
Homo sapiens (Human)
Description:
Human Foxm BDB (235-327 aa)
Residue:
93
Sequence:
ERPPYSYMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETSANGKVSFWTIHPSANRYLTLDQVFKPL
  
Inhibitor
Name:
BDBM218821
Synonyms:
CID 2748293
Type:
Small organic molecule
Emp. Form.:
C15H17N3O4S
Mol. Mass.:
335.378
SMILES:
CC(C)OC(=O)C1=C(C)NC(=S)NC1c1ccc(cc1)[N+]([O-])=O |c:6|
Structure:
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