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Target
Interleukin-2
Ligand
BDBM161818
Substrate
n/a
Meas. Tech.
IL-2 ELISA Assay
EC50
<100±n/a nM
Citation
 Singh, R; Duncton, M; Zhang, J; Alvarez, S; Tso, K; Holland, S; Yen, R; Kolluri, R; Heckrodt, T; Chen, Y; Masuda, E; Li, H; Payan, DG; Kelley, R Protein kinase C inhibitors and uses thereof US Patent  US9682976 Publication Date 6/20/2017 
Target
Name:
Interleukin-2
Synonyms:
IL-2 | IL2 | IL2_HUMAN | INN=Aldesleukin | Interleukin-2 | Interleukin-2 (IL-2) | T-cell growth factor | TCGF
Type:
Enzyme
Mol. Mass.:
17630.05
Organism:
Homo sapiens (Human)
Description:
P60568
Residue:
153
Sequence:
MYRMQLLSCIALSLALVTNSAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT
  
Inhibitor
Name:
BDBM161818
Synonyms:
US9682976, 255
Type:
Small organic molecule
Emp. Form.:
C27H33F2N9O2
Mol. Mass.:
553.6068
SMILES:
CC1(C)C[C@@H](C[C@@H]2CCCN12)Nc1nc(Nc2cc(c(OC3COC3)cc2F)-n2nnnc2C2CC2)ncc1F |r|
Structure:
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