Reaction Details Report a problem with these data
Target
Alpha-glucosidase MAL12
Ligand
BDBM243072
Substrate
n/a
Meas. Tech.
α-glucosidase Inhibitory Activity Assay
pH
7±n/a
Temperature
298.15±n/a K
IC50
>3.00e+5±n/a nM
Comments
extracted
Citation
 Kashima, Y; Yamaki, H; Suzuki, T; Miyazawa, M Structure-activity relationships of bergenin derivatives effect on a-glucosidase inhibition. J Enzyme Inhib Med Chem 28:1162-70 (2013) [PubMed]  Article 
Target
Name:
Alpha-glucosidase MAL12
Synonyms:
α-Glucosidase | MAL12 | MAL12_YEAST | MAL1S | Maltase | alpha-Glucosidase (α-Glucosidase)
Type:
Protein
Mol. Mass.:
68084.32
Organism:
Saccharomyces cerevisiae
Description:
P53341
Residue:
584
Sequence:
MTISDHPETEPKWWKEATIYQIYPASFKDSNNDGWGDLKGITSKLQYIKDLGVDAIWVCPFYDSPQQDMGYDISNYEKVWPTYGTNEDCFELIDKTHKLGMKFITDLVINHCSTEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSFFGGSAWTFDETTNEFYLRLFASRQVDLNWENEDCRRAIFESAVGFWLDHGVDGFRIDTAGLYSKRPGLPDSPIFDKTSKLQHPNWGSHNGPRIHEYHQELHRFMKNRVKDGREIMTVGEVAHGSDNALYTSAARYEVSEVFSFTHVEVGTSPFFRYNIVPFTLKQWKEAIASNFLFINGTDSWATTYIENHDQARSITRFADDSPKYRKISGKLLTLLECSLTGTLYVYQGQEIGQINFKEWPIEKYEDVDVKNNYEIIKKSFGKNSKEMKDFFKGIALLSRDHSRTPMPWTKDKPNAGFTGPDVKPWFLLNESFEQGINVEQESRDDDSVLNFWKRALQARKKYKELMIYGYDFQFIDLDSDQIFSFTKEYEDKTLFAALNFSGEEIEFSLPREGASLSFILGNYDDTDVSSRVLKPWEGRIYLVK
  
Inhibitor
Name:
BDBM243072
Synonyms:
Anisic acid
Type:
Small organic molecule
Emp. Form.:
C8H8O3
Mol. Mass.:
152.1473
SMILES:
COc1ccc(cc1)C(O)=O
Structure:
Search PDB for entries with ligand similarity: