Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 3JWK
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

LigandPNGBDBM18496(JMC517532 Compound 10 | Propargyl-substituted anti...)
Affinity DataIC50: 2.91E+4nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH oxidation at an absorbance of 340 nm over several minutes. All...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

LigandPNGBDBM18496(JMC517532 Compound 10 | Propargyl-substituted anti...)
Affinity DataIC50: 2.91E+4nMAssay Description:Inhibition of wild type Bacillus anthracis recombinant DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

LigandPNGBDBM18496(JMC517532 Compound 10 | Propargyl-substituted anti...)
Affinity DataKi:  9.81E+3nMAssay Description:Inhibition of wild type Bacillus anthracis recombinant DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)