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Found
1
Enz. Inhib. hit(s) for PDB:
3MDT
Target
Cholesterol 24-hydroxylase
(Human)
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50333117
((2R,3S)-2,3-bis(2,4-difluorophenyl)-1-(1H-1,2,4-tr...)
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Affinity Data
IC50: 1.00E+4nM
Assay Description:
Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...
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Target Info
PDB
UniProtKB/SwissProt
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Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
4/20/2024
Entry Details
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PubMed
PDB
3D Structure (crystal)
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