TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Inhibition of CYP46A1 (unknown origin)More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 106nMAssay Description:Inhibition of CYP46A1 (unknown origin)More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 258nMAssay Description:Inhibition of CYP46A1 (unknown origin)More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 7.30E+3nMAssay Description:Binding affinity to full length human CYP46A1 expressed in Escherichia coli DH5alpha as cholesterol-24 hydroxylation using cholesterol as substrate i...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand Info
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand Info
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand InfoPDB
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand Info
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand Info
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand Info
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand Info
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 6.10nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand Info
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 6.90nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 7.10nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 7.30nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 7.40nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 7.40nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 7.40nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 7.80nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand Info
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand Info
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 8.10nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 8.5nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 8.80nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 9.5nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand Info
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand Info
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand Info
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand Info
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand InfoPDB
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair