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Found
1
Enz. Inhib. hit(s) for PDB:
3QLY
Target
Dihydrofolate reductase
(Yeast)
University of Connecticut
Ligand
BDBM50329608
(Propargyl-substituted antifolate, 14 | CHEMBL12303...)
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Affinity Data
IC50: 11nM
Assay Description:
Enzyme activity assay were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over 5 min.
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Target Info
PDB
KEGG
UniProtKB/TrEMBL
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Ligand Info
CHEMBL
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PC cid
PC sid
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Similars
In Depth
Date in BDB:
11/15/2011
Entry Details
Article
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PubMed
PDB
3D Structure (crystal)
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