Report error Found 20 Enz. Inhib. hit(s) for PDB: 3TT0
Affinity DataIC50: 0.5nMAssay Description:Inhibition of wild-type FGFR1 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 0.5nMAssay Description:Inhibition of wild-type FGFR2 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.590nMAssay Description:Inhibition of N-terminal GST-tagged human FGFR1 cytoplasmic domain (398-822 AA) expressed in baculovirus using FAM-labelled peptide as substrate pre-...More data for this Ligand-Target Pair
Affinity DataIC50: 0.590nMAssay Description:Inhibition of N-terminal GST-tagged human FGFR1 cytoplasmic domain (398-822 AA) expressed in baculovirus using FAM-labelled peptide as substrate pre-...More data for this Ligand-Target Pair
Affinity DataIC50: 0.680nMAssay Description:Inhibition of FGFR2 N549H mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of recombinant FGFR1More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant FGFR1 (unknown origin) using peptidic substrates in presence of ATP by Kinase-Glo luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Recombinant FGFR1 (2.5 nM), or FGFR4 (12 nM) was prepared as a mixture with substrate KKKSPGEYVNIEFG (SEQ ID NO:1) (20 μM, FGFR1 substrate); Pol...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Recombinant FGFR1 (2.5 nM), FGFR2 (1 nM), FGFR3 (5 nM), or FGFR4 (12 nM) (Invitrogen ) was prepared as a mixture with substrate KKKSPGEYVNIEFG (SEQ I...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant FGFR2 (unknown origin) using peptidic substrates in presence of ATP by Kinase-Glo luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:Recombinant FGFR1 (2.5 nM), or FGFR4 (12 nM) was prepared as a mixture with substrate KKKSPGEYVNIEFG (SEQ ID NO:1) (20 μM, FGFR1 substrate); Pol...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant FGFR2More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of FGFR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of FGFR2 juxtamembrane domain-mediated proliferation of mouse BAF3 cells transformed with TEL-Kinase constructMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of recombinant human FGFR1 using biotin-EQEDEPEGDYFEWLE-amide as substrate preincubated for 5 to 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of FGFR1-mediated proliferation of mouse BAF3 cells transformed with TEL-Kinase constructMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Inhibition of wild type FGFR1 expressed in HEK293 cells assessed as inhibition of autophosphorylation of tyrosine residue after 40 mins by ELISA assa...More data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Inhibition of wild type FGFR2 expressed in HEK293 cells assessed as inhibition of autophosphorylation of tyrosine residue after 40 mins by ELISA assa...More data for this Ligand-Target Pair
Affinity DataIC50: 759nMAssay Description:Inhibition of FGFR1 V561M mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair