Report error Found 2 Enz. Inhib. hit(s) for PDB: 4M52
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Weill Cornell Medical College
Weill Cornell Medical College
Affinity DataKi: 140nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica
US Patent
Academia Sinica
US Patent
Affinity DataIC50: 960nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair

3D Structure (crystal)