Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 4XWY
TargetSepiapterin reductase(Human)
Solace Pharmaceuticals

US Patent
LigandPNGBDBM187258(US9169234, 23)
Affinity DataIC50: 11nMpH: 6.5 T: 2°CAssay Description:To screen for SPR inhibition, a biochemical assay based on LC/MS (and chromogenic) read-out has been developed. The LC/MS assay monitors the product ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetSepiapterin reductase(Human)
Solace Pharmaceuticals

US Patent
LigandPNGBDBM187258(US9169234, 23)
Affinity DataIC50: 12nMpH: 6.5 T: 2°CAssay Description:To screen for SPR inhibition, a biochemical assay based on LC/MS (and chromogenic) read-out has been developed. The LC/MS assay monitors the product ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetSepiapterin reductase(Human)
Solace Pharmaceuticals

US Patent
LigandPNGBDBM187258(US9169234, 23)
Affinity DataIC50: 310nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)