Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 5KOT
TargetRenin(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50273160(IMARIKIREN)
Affinity DataIC50: 0.430nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRenin(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50273160(IMARIKIREN)
Affinity DataIC50: 0.840nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRenin(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50273160(IMARIKIREN)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of renin in human plasma by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRenin(Rhesus macaque)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50273160(IMARIKIREN)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of renin in monkey plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)