Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 5OWC
TargetGroup 10 secretory phospholipase A2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50366784(CHEMBL4171084)
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGroup 10 secretory phospholipase A2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50366784(CHEMBL4171084)
Affinity DataIC50: 26nMAssay Description:Inhibition of sPLA2-10 (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate pretreated for 20 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGroup 10 secretory phospholipase A2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50366784(CHEMBL4171084)
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using HDL as substrate pretreated for 20 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGroup 10 secretory phospholipase A2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50366784(CHEMBL4171084)
Affinity DataIC50: 310nMAssay Description:Inhibition of recombinant human sPLA2-10 using human HDL as substrate pretreated for 20 mins followed by substrate addition and measured after 60 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)