Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) for PDB: 5P9F
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50388183(CHEMBL2057915)
Affinity DataEC50:  380nMAssay Description:Inhibition of BTK in human whole blood B-cells assessed as inhibition of both anti-IgD-stimulated CD69 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50388183(CHEMBL2057915)
Affinity DataEC50:  350nMAssay Description:Inhibition of BTK in human whole blood basophils assessed as inhibition of both anti-IgE-stimulated CD63 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50388183(CHEMBL2057915)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human BTK by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50388183(CHEMBL2057915)
Affinity DataIC50: 6nMAssay Description:Inhibition of BTK (unknown origin) by Lanthascreen methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50388183(CHEMBL2057915)
Affinity DataIC50: 14nMAssay Description:Inhibition of BTK (unknown origin) by Lanthascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50388183(CHEMBL2057915)
Affinity DataIC50: 60nMAssay Description:Inhibition of BTK-mediated CD86 surface expression in Balb/c mouse splenocytes preincubated for 60 mins before F(ab')2 anti-mouse IgM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)