Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) for PDB: 5ZSG
TargetToll-like receptor 7(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50320067(1-(4-amino-2-((ethylamino)methyl)-1H-imidazo[4,5-c...)
Affinity DataEC50:  8.60nMAssay Description:Agonist activity at human TLR7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 7(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50320067(1-(4-amino-2-((ethylamino)methyl)-1H-imidazo[4,5-c...)
Affinity DataEC50:  172nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetToll-like receptor 7(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50320067(1-(4-amino-2-((ethylamino)methyl)-1H-imidazo[4,5-c...)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at human TLR7 expressed in NF-kappaB-stimulated HEK293 cells assessed as induction of secreted alkaline phosphatase expression by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 7(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50320067(1-(4-amino-2-((ethylamino)methyl)-1H-imidazo[4,5-c...)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at TLR7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 7(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50320067(1-(4-amino-2-((ethylamino)methyl)-1H-imidazo[4,5-c...)
Affinity DataEC50:  3.34E+3nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2021
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetToll-like receptor 7(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50320067(1-(4-amino-2-((ethylamino)methyl)-1H-imidazo[4,5-c...)
Affinity DataEC50:  3.34E+3nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2020
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetToll-like receptor 7(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50320067(1-(4-amino-2-((ethylamino)methyl)-1H-imidazo[4,5-c...)
Affinity DataEC50:  3.34E+3nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetToll-like receptor 7(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50320067(1-(4-amino-2-((ethylamino)methyl)-1H-imidazo[4,5-c...)
Affinity DataEC50:  3.34E+3nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2020
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetToll-like receptor 7(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50320067(1-(4-amino-2-((ethylamino)methyl)-1H-imidazo[4,5-c...)
Affinity DataEC50:  4.00E+3nMAssay Description:Agonist activity at human TLR7 in HEK-Blue hTLR7 cells incubated for 18 hrs by QUANTI-Blue reagent based SEAP reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)